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Dokument 3311Titel:
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Warning: Use of undefined constant titel_deutsch - assumed 'titel_deutsch' (this will throw an Error in a future version of PHP) in /www/htdocs/w00ea1bb/aerzteneu/Backup/Kopie/datenbank-ergebnis.php on line 528

Warning: Use of undefined constant titel_englisch - assumed 'titel_englisch' (this will throw an Error in a future version of PHP) in /www/htdocs/w00ea1bb/aerzteneu/Backup/Kopie/datenbank-ergebnis.php on line 528
Normal lysosomal morphology and function in LAMP-1-deficient mice
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Warning: Use of undefined constant bereiche - assumed 'bereiche' (this will throw an Error in a future version of PHP) in /www/htdocs/w00ea1bb/aerzteneu/Backup/Kopie/datenbank-ergebnis.php on line 530

Bereich:
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Biochemie, Molekularbiologie
Tiere:
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Warning: Use of undefined constant tieranzahl - assumed 'tieranzahl' (this will throw an Error in a future version of PHP) in /www/htdocs/w00ea1bb/aerzteneu/Backup/Kopie/datenbank-ergebnis.php on line 534

Warning: Use of undefined constant tieranzahl - assumed 'tieranzahl' (this will throw an Error in a future version of PHP) in /www/htdocs/w00ea1bb/aerzteneu/Backup/Kopie/datenbank-ergebnis.php on line 535

Warning: Use of undefined constant tieranzahl - assumed 'tieranzahl' (this will throw an Error in a future version of PHP) in /www/htdocs/w00ea1bb/aerzteneu/Backup/Kopie/datenbank-ergebnis.php on line 535
18
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Mäuse
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(
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mindestens)
Jahr: 1999

Versuchsbeschreibung:
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Es wird eine Mäuselinie "erstellt", die einen Mangel an einem Protein hat, aber klinisch keine Veränderungen aufweist.

Bereich:
Warning: Use of undefined constant bereiche - assumed 'bereiche' (this will throw an Error in a future version of PHP) in /www/htdocs/w00ea1bb/aerzteneu/Backup/Kopie/datenbank-ergebnis.php on line 543

Warning: Use of undefined constant bereiche - assumed 'bereiche' (this will throw an Error in a future version of PHP) in /www/htdocs/w00ea1bb/aerzteneu/Backup/Kopie/datenbank-ergebnis.php on line 543
Biochemie, Molekularbiologie

Originaltitel: Normal lysosomal morphology and function in LAMP-1-deficient mice

Autoren:
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Nicole Andrejewski (1)* , Gundula Guhde (1) , Yoshitaka Tanaka (1) , Kurt von Figura (1) , Paul Saftig (1) , Eeva-Liisa Punnonen (2) , Dieter Hartmann (3) , Renate Lüllmann-Rauch (3)

Institute:
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(1)*Zentrum Biochemie und Zellbiologie, Abteilung Biochemie II, Uni Göttingen, (2) University of Helsinki, Finnland, und (3) Anatomisches Institut, CAU Kiel

Zeitschrift:
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The Journal of Biological Chemistry 1999: 274(18), 12692-12701

Land:
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Deutschland

Art der Veröffentlichung:
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Fachzeitschrift

Dokumenten-ID:
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1825


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Dokument 3312Titel:
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Warning: Use of undefined constant titel_deutsch - assumed 'titel_deutsch' (this will throw an Error in a future version of PHP) in /www/htdocs/w00ea1bb/aerzteneu/Backup/Kopie/datenbank-ergebnis.php on line 528

Warning: Use of undefined constant titel_englisch - assumed 'titel_englisch' (this will throw an Error in a future version of PHP) in /www/htdocs/w00ea1bb/aerzteneu/Backup/Kopie/datenbank-ergebnis.php on line 528
Synergism of the malononitrilamides 279 and 715 with cyclosporine A in the induction of long-term cardiac allograft survival
Warning: Use of undefined constant hintergrund - assumed 'hintergrund' (this will throw an Error in a future version of PHP) in /www/htdocs/w00ea1bb/aerzteneu/Backup/Kopie/datenbank-ergebnis.php on line 529

Warning: Use of undefined constant bereiche - assumed 'bereiche' (this will throw an Error in a future version of PHP) in /www/htdocs/w00ea1bb/aerzteneu/Backup/Kopie/datenbank-ergebnis.php on line 530

Bereich:
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Immunologie, Transplantationsmedizin
Tiere:
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Warning: Use of undefined constant tierart_id - assumed 'tierart_id' (this will throw an Error in a future version of PHP) in /www/htdocs/w00ea1bb/aerzteneu/Backup/Kopie/datenbank-ergebnis.php on line 533
Ratten (Anzahl unbekannt)
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(
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Anzahl unbekannt)
Jahr: 1998

Versuchsbeschreibung:
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Die Herzen von Ratten werden in die Bauchhöhle von anderen Ratten gepflanzt (zusätzlich zum eigenen Herz). Es werden Immunsuppressiva verabreicht. Tiere, die das Herz nach 100 Tagen noch nicht abgestoßen haben, bekommen zusätzlich ein Stück Schwanzhaut transplantiert.

Bereich:
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Warning: Use of undefined constant bereiche - assumed 'bereiche' (this will throw an Error in a future version of PHP) in /www/htdocs/w00ea1bb/aerzteneu/Backup/Kopie/datenbank-ergebnis.php on line 543
Immunologie, Transplantationsmedizin

Originaltitel: Synergism of the malononitrilamides 279 and 715 with cyclosporine A in the induction of long-term cardiac allograft survival

Autoren:
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J.K. Lindner (1)* , Niko Zantl (2)

Institute:
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(1)*Hoechst Marion Roussel Deutschland GmbH, Wiesbaden, und (2) Institut für Chirurgie, Klinikum rechts der Isar, TU München

Zeitschrift:
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Transplantation International 1998: 11(1), 303-309

Land:
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Deutschland

Art der Veröffentlichung:
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Fachzeitschrift

Dokumenten-ID:
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1824


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Dokument 3313Titel:
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Warning: Use of undefined constant titel_deutsch - assumed 'titel_deutsch' (this will throw an Error in a future version of PHP) in /www/htdocs/w00ea1bb/aerzteneu/Backup/Kopie/datenbank-ergebnis.php on line 528

Warning: Use of undefined constant titel_englisch - assumed 'titel_englisch' (this will throw an Error in a future version of PHP) in /www/htdocs/w00ea1bb/aerzteneu/Backup/Kopie/datenbank-ergebnis.php on line 528
Regulation of alloreactivity in the popliteal lymph node assay by the new immunosuppressants: malononitrilamides
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Warning: Use of undefined constant bereiche - assumed 'bereiche' (this will throw an Error in a future version of PHP) in /www/htdocs/w00ea1bb/aerzteneu/Backup/Kopie/datenbank-ergebnis.php on line 530

Bereich:
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Immunologie
Tiere:
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Warning: Use of undefined constant tierart_id - assumed 'tierart_id' (this will throw an Error in a future version of PHP) in /www/htdocs/w00ea1bb/aerzteneu/Backup/Kopie/datenbank-ergebnis.php on line 533
Ratten (Anzahl unbekannt)
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(
Warning: Use of undefined constant tierdetails - assumed 'tierdetails' (this will throw an Error in a future version of PHP) in /www/htdocs/w00ea1bb/aerzteneu/Backup/Kopie/datenbank-ergebnis.php on line 536
Anzahl unbekannt)
Jahr: 1998

Versuchsbeschreibung:
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Milzzellen von Ratten werden in die Hinterpfote anderer Ratten gespritzt, um eine Reaktion des Immunsystems hervorzurufen. Verschiedene Immunsuppressiva werden getestet.

Bereich:
Warning: Use of undefined constant bereiche - assumed 'bereiche' (this will throw an Error in a future version of PHP) in /www/htdocs/w00ea1bb/aerzteneu/Backup/Kopie/datenbank-ergebnis.php on line 543

Warning: Use of undefined constant bereiche - assumed 'bereiche' (this will throw an Error in a future version of PHP) in /www/htdocs/w00ea1bb/aerzteneu/Backup/Kopie/datenbank-ergebnis.php on line 543
Immunologie

Originaltitel: Regulation of alloreactivity in the popliteal lymph node assay by the new immunosuppressants: malononitrilamides

Autoren:
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H.U. Schorlemmer (1)* , R. Kurrle (1) , E. Ruuth (2)

Institute:
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(1)*Hoechst Marion Roussel Deutschland GmbH, Wiesbaden, und (2) Roussel UCLAF, Paris-Romainville, Frankreich

Zeitschrift:
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Transplantation International 1998: 11(1), 448-451

Land:
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Deutschland

Art der Veröffentlichung:
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Fachzeitschrift

Dokumenten-ID:
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1823


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Dokument 3314Titel:
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Warning: Use of undefined constant titel_deutsch - assumed 'titel_deutsch' (this will throw an Error in a future version of PHP) in /www/htdocs/w00ea1bb/aerzteneu/Backup/Kopie/datenbank-ergebnis.php on line 528

Warning: Use of undefined constant titel_englisch - assumed 'titel_englisch' (this will throw an Error in a future version of PHP) in /www/htdocs/w00ea1bb/aerzteneu/Backup/Kopie/datenbank-ergebnis.php on line 528
Malonitrilamides syngistically prevent acute and treat ongoing skin allograft rejection with cyclosporine
Warning: Use of undefined constant hintergrund - assumed 'hintergrund' (this will throw an Error in a future version of PHP) in /www/htdocs/w00ea1bb/aerzteneu/Backup/Kopie/datenbank-ergebnis.php on line 529

Warning: Use of undefined constant bereiche - assumed 'bereiche' (this will throw an Error in a future version of PHP) in /www/htdocs/w00ea1bb/aerzteneu/Backup/Kopie/datenbank-ergebnis.php on line 530

Bereich:
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Immunologie, Transplantationsmedizin
Tiere:
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Ratten (Anzahl unbekannt)
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(
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Anzahl unbekannt)
Jahr: 1998

Versuchsbeschreibung:
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Transplantation von Hautstücken vom Schwanz auf andere Ratten. Testen verschiedener Immunsuppressiva.

Bereich:
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Warning: Use of undefined constant bereiche - assumed 'bereiche' (this will throw an Error in a future version of PHP) in /www/htdocs/w00ea1bb/aerzteneu/Backup/Kopie/datenbank-ergebnis.php on line 543
Immunologie, Transplantationsmedizin

Originaltitel: Malonitrilamides syngistically prevent acute and treat ongoing skin allograft rejection with cyclosporine

Autoren:
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H.U. Schorlemmer (1)* , R. Kurrle (1) , E. Ruuth (2)

Institute:
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(1)*Hoechst Marion Roussel Deutschland GmbH, Wiesbaden, und (2) Roussel UCLAF, Paris-Romainville, Frankreich

Zeitschrift:
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Transplantation International 1998: 11(1), 340-344

Land:
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Deutschland

Art der Veröffentlichung:
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Fachzeitschrift

Dokumenten-ID:
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1822


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Dokument 3315Titel:
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Immunomodulatory activity of malononitrilamides, derivatives of leflunomide´s primary metabolite, on models of experimental rheumatoid arthritis
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Warning: Use of undefined constant bereiche - assumed 'bereiche' (this will throw an Error in a future version of PHP) in /www/htdocs/w00ea1bb/aerzteneu/Backup/Kopie/datenbank-ergebnis.php on line 530

Bereich:
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Rheumatologie
Tiere:
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Tiere verschiedener Arten (Anzahl unbekannt)
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(
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Ratten, Mäuse (Anzahl unbekannt))
Jahr: 1998

Versuchsbeschreibung:
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Es werden 2 verschiedene Rheuma-"Modelle" verwendet. Bei Ratten wird durch Injektion von Bakterien in eine Hinterpfote eine Gelenkentzündung hervorgerufen. Die Mäuse entwickeln eine Gelenkentzündung als Folge einer Autoimmunkrankheit, bei der das Immunsystem Zellen des eigenen Körpers zerstört. Es werden Immunsuppressiva getestet. Besonders für unbehandelte Kontrolltiere ein schmerzhafter Versuch.

Bereich:
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Rheumatologie

Originaltitel: Immunomodulatory activity of malononitrilamides, derivatives of leflunomide´s primary metabolite, on models of experimental rheumatoid arthritis

Autoren:
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H.U. Schorlemmer (1)* , R.R. Bartlett (1) , R. Schleyerbach (1)

Institute:
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(1)*Hoechst Marion Roussel Deutschland GmbH, Wiesbaden

Zeitschrift:
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Transplantation Proceedings 1998: 30, 4137-4139

Land:
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Deutschland

Art der Veröffentlichung:
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Fachzeitschrift

Dokumenten-ID:
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1821


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Dokument 3316Titel:
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Modulation of immunoglobulin dysregulation in graft versus host- and systemic lupus erythematosus-like diseases by malononitrilamides
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Warning: Use of undefined constant bereiche - assumed 'bereiche' (this will throw an Error in a future version of PHP) in /www/htdocs/w00ea1bb/aerzteneu/Backup/Kopie/datenbank-ergebnis.php on line 530

Bereich:
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Immunologie
Tiere:
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Mäuse (Anzahl unbekannt)
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(
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Anzahl unbekannt)
Jahr: 1998

Versuchsbeschreibung:
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Es werden immunologische Krankheitssymptome hervorgerufen (Milz- und Lymphknotenschwellung, Nierenentzündung) und Immunsuppressiva getestet. Unbehandelte Kontrolltiere sterben innerhalb von 13 Wochen. Die Versuche dauern mehrere Monate.

Bereich:
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Immunologie

Originaltitel: Modulation of immunoglobulin dysregulation in graft versus host- and systemic lupus erythematosus-like diseases by malononitrilamides

Autoren:
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H.U. Schorlemmer (1)* , R.R. Bartlett (1)

Institute:
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(1)*Hoechst Marion Roussel Deutschland GmbH, Wiesbaden

Zeitschrift:
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Transplantation Proceedings 1998: 30, 4153-4155

Land:
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Deutschland

Art der Veröffentlichung:
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Fachzeitschrift

Dokumenten-ID:
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1820


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Dokument 3317Titel:
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Combination therapy of malononitrilamides and tacrolimus (FK 506) induced lonf-term xenograft survival
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Bereich:
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Xenotransplantationsforschung
Tiere:
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Tiere verschiedener Arten (Anzahl unbekannt)
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(
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Ratten, Mäuse (Anzahl unbekannt))
Jahr: 1998

Versuchsbeschreibung:
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Transplantation von Hautstücken von Mäusen auf den Schwanz von Ratten. Testen verschiedener Immunsuppressiva.

Bereich:
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Warning: Use of undefined constant bereiche - assumed 'bereiche' (this will throw an Error in a future version of PHP) in /www/htdocs/w00ea1bb/aerzteneu/Backup/Kopie/datenbank-ergebnis.php on line 543
Xenotransplantationsforschung

Originaltitel: Combination therapy of malononitrilamides and tacrolimus (FK 506) induced lonf-term xenograft survival

Autoren:
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H.U. Schorlemmer (1)* , R. Kurrle (1)

Institute:
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(1)*Hoechst Marion Roussel Deutschland GmbH, Wiesbaden

Zeitschrift:
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Transplantation Proceedings 1998: 30, 4170-4173

Land:
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Deutschland

Art der Veröffentlichung:
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Fachzeitschrift

Dokumenten-ID:
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1819


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Dokument 3318Titel:
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Warning: Use of undefined constant titel_deutsch - assumed 'titel_deutsch' (this will throw an Error in a future version of PHP) in /www/htdocs/w00ea1bb/aerzteneu/Backup/Kopie/datenbank-ergebnis.php on line 528

Warning: Use of undefined constant titel_englisch - assumed 'titel_englisch' (this will throw an Error in a future version of PHP) in /www/htdocs/w00ea1bb/aerzteneu/Backup/Kopie/datenbank-ergebnis.php on line 528
Anatomical connections of auditory and lateral line areas of the dorsal telencephalon (Dm) in the osteoglossomorph teleost, Gnathonemus petersii
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Bereich:
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Zooanatomie, Zoophysiologie
Tiere:
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16
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Fische
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(
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elektrische Fische)
Jahr: 1999

Versuchsbeschreibung:
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Bei den aus Afrika importierten Fischen wird der Schädel eröffnet, und es werden Ableitungen am Gehirn vorgenommen. Finale Narkose.

Bereich:
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Zooanatomie, Zoophysiologie

Originaltitel: Anatomical connections of auditory and lateral line areas of the dorsal telencephalon (Dm) in the osteoglossomorph teleost, Gnathonemus petersii

Autoren:
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Gerhard von der Emde (1)* , James C. Prechtl (2)

Institute:
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(1)*Zoologisches Institut, Uni Bonn, und (2) Scripps Institution of Oceanography, University of California San Diego, La Jolla, CA, USA

Zeitschrift:
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Brain Research 1999: 818, 355-367

Land:
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Deutschland

Art der Veröffentlichung:
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Fachzeitschrift

Dokumenten-ID:
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1818


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Dokument 3319Titel:
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Influence of fentanyl, alfentanil and sufentanil on motor evoked potentials
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Bereich:
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Anästhesiologie
Tiere:
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30
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Kaninchen
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Jahr: 1999

Versuchsbeschreibung:
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Das Gehirn wird über eingepflanzte Elektroden gereizt, während verschiedene Opioide verabreicht werden. Versuche in (finaler?) Narkose.

Bereich:
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Anästhesiologie

Originaltitel: Influence of fentanyl, alfentanil and sufentanil on motor evoked potentials

Autoren:
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Christof Thees (1)* , Joachim Nadstawek (1) , Michael Hanisch (1) , Ronald Juntke (1) , Andreas Hoeft (1) , Josef Zentner (2) , Ulrich Pechstein (2) , Kai-Michael Scheufler (2)

Institute:
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(1)*Klinik und Poliklinik für Anästhesiologie, Uni Bonn, und (2) Institut für Neurochirurgie, Medizinisches Zentrum, Uni Bonn

Zeitschrift:
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Journal of Neurosurgical Anaesthesiology 1999: 11(2), 112-118

Land:
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Deutschland

Art der Veröffentlichung:
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Fachzeitschrift

Dokumenten-ID:
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1817


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Dokument 3320Titel:
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Microbial translocation and impairment of mucosal immunity induced by an elemental diet in rats is prevented by selective decontamination of the digestive tract
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Warning: Use of undefined constant bereiche - assumed 'bereiche' (this will throw an Error in a future version of PHP) in /www/htdocs/w00ea1bb/aerzteneu/Backup/Kopie/datenbank-ergebnis.php on line 530

Bereich:
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Gastroenterologie
Tiere:
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45
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Mäuse
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Jahr: 1998

Versuchsbeschreibung:
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Sieben Tage nach Fütterung einer bestimmten Diät werden die Ratten getötet und ihr Darm untersucht.

Bereich:
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Gastroenterologie

Originaltitel: Microbial translocation and impairment of mucosal immunity induced by an elemental diet in rats is prevented by selective decontamination of the digestive tract

Autoren:
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Georg Späth (1)* , Andreas Hirner (1)

Institute:
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(1)*Institut für Chirurgie, Uni Bonn

Zeitschrift:
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European Journal of Surgery 1998: 164, 223-228

Land:
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Deutschland

Art der Veröffentlichung:
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Fachzeitschrift

Dokumenten-ID:
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1816


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